Yeah, so a few reasons. And this was certainly something one of the reviewers of the paper asks, like, why these? So I was like, Oh, I guess I should guess it's actually have a reason other than just I think they're interesting, but I think that's, that's it, they come up so regularly. So every, every press release about autism research, like, you know, so and so has such and such Institute has gotten so many millions of dollars for studying microbiome stuff. Every press release, every, you know, kind of like women's magazine article about your gut garden. Always, all of the kind of introductory matter that tends to happen at the beginning of articles, it will frequently have this like list of like microbiome science is really emerging. And we now think it offers cures for I don't know the list of strain of conditions. You know, what conditions like Crohn's colorectal cancer like, like very serious conditions. And interestingly, obesity and autism always show up on these lists. And what I find interesting about them is one, there's controversy about whether Obesity is a disease. It's been named a disease, obviously, by the World Health Organization by the American Medical Association, so on so forth, but obviously, there's been a lot of pushback about whether obesity in and of itself, as a state of human beings ought to be considered to see. So that's, I find that interesting that like, you know, we keep mentioning this thing, there's controversy about it. And similarly with autism, there's there's a similar, very strong pushback from Autistic Self Advocates about like, you know, certainly this is something that makes us this different, but like, as a disease, disease has connotations that, that don't necessarily seem to they don't necessarily seem to fit. And so I think to some extent, I chose them because they were really good examples of this kind of work of normalcy at play. Were the only reason they're on this list, like obesity is basically defined according to BMI. So it's, it has nothing about actual health status. It's just the statement about the relationship of health and weight. And similarly with autism, I mean, of course, it's defined in psychiatric literature, it's defined in the DSM. But again, with the sort of single minded focus of the research is on behaviors, you just see this again and again and again. Now with autism, there's a lot of studies that do show a correlation between being autistic and having and having various forms of gut issues. Like they're just really common. The exact prevalence varies a lot depending on the study. But this this correlation kind of comes up again and again. And so you can pretty and you can pretty reasonably ask, you know, would it be helpful if we found sort of useful, useful treatments for this? But the focus is so often on the behaviors. So for example, autistic people frequently stim right So kind of repetitive movements and motions and so forth that are aimed at sort of self soothing, and, you know, just interacting with the environment. And the and so the one of the measures of well, did this microbiome therapy work as well? Was there less stimming? And did the person make more eye contact? It's like, Well, are we worried about this? Or are we worried about whether their stomachs feel okay? And it's one thing, and maybe on a bit of a tangent to this pipe, it's one thing when this is research that's being done on, you know, three year olds who maybe can't fill out a form with a Likert scale on it. But some of this research is then done on adults. And you're like, Well, you could just ask them, how they're, how their stomachs feel? And they would they would tell you, yeah, so these two examples are just seemed particularly good. And also, it's in these two examples that you can see this this work of the the imperative normalcy really strongly, and, and in which the sort of focus on things like behavior and appearance is is strongest. At some point, at some point, I think I would find it interesting to go into how well, the focus of microbiome therapies actually hits on the particular concerns of people with more definite gut issues that are more sort of definitely diseases. But I would be reluctant to do so by myself, I would want to do so probably with a collaborator who was deeply knowledgeable, ideally, you know, someone with like lived experience of having that so that they could, you know, so we could work together on what priorities ought to be. So I haven't looked deeply into that side of things. I did get a question through the review process about why I didn't also look at research around microbiomes, and microbiome therapies and moods. So for example, there's a lot of research developing right now, especially for people like John Cryan, in Ireland, and Timothy Dinen [both at University College Cork], I don't know how to say his last name, also in Ireland, they've been doing a lot of research about microbiome and mood. And I think that's, I think that's really interesting as well. They've primarily got mouse studies, which, you know, always are sort of like, how do you know if a mouse is depressed? How do you know if a mouse is anxious, but they've got some starter pilot human studies going in which they, you know, have sort of tentative reasons to go forward. I think that's definitely something to keep an eye on. But this sort of question about an imperative of normalcy. And something like depression, I think, raises a pile of other issues that I didn't want to pull into this particular paper.