Well, one of the reasons why we like this as an issue is because I think that intuitions can go both ways, relatively easily. We did speak with people, like clinical genomicists to get a picture of things. And one way you could see is that, well, we administer these tests, that one, I remember someone saying that there's no other diagnostic tests that we administer, that we know so little about. And, and yet, we give a test like this. And so insofar as we do that, yes, I feel an obligation to my patients in order to continue to reanalyze or reinterpret the data or do anything, basically, to, eventually to, to give us the best chances of getting a diagnosis, even if that is looking at it every six months. So be it. But then, the other side of the equation is is that well, if we really don't understand this technology, and if the fact that we are providing patients with information that is ultimately uncertain, or not ultimately uncertain, uncertain at the time, but may well be, we may well have further knowledge, diagnostic knowledge about it in the future. Well, if this is such a problem, maybe we shouldn't be giving them the test. Now, I don't think you've got to find basically a middle ground between those two things, because doctors will say no, no, this is the best test we have. We have to give it to them and say yes. But does that imply that you have to therefore keeping keep on reanalyzing, or reinterpreting the variant classifications in order to get a diagnosis or give yourself the best chances? Our answer is ultimately, a mixed one. But no, there's no general obligation and we analyse three, well, we analyse three sources, which may give us an ethical obligation we. And so one of them is an ongoing duty of care,  pay doctors or medical professionals have ongoing duty of care to their patients. Another one is what we call systemic error risk. And the last one is diagnostic equity. So we look at this situation through these three frames. And we argue that insofar as ongoing duties of care are concerned, no, there's no general requirement that you continuously or regularly or  actively and regularly reinterpret genomic varying classifications. However, in certain cases, there are.